Archive for December, 2012

DERMATOGLYPHICS IN THE IDENTIFICATION OF WOMEN EITHER WITH OR AT RISK FOR BREAST CANCER – Shivaji B. Sukre, M Laeeque, A. Mahajan, Shilpa N.Shewale

 Abstract    Dermatoglyphics is the study of epidermal ridges of palms, soles and fingers. Dermatoglyphic pattern has been studied in various diseases.  In the present study Dermatoglyphic pattern was studied in Breast cancer, 50 Breast cancer patients and 50 normal subjects (free from disease of Breast cancer or family history) were selected and prints of palms and fingers were take.  The prints were analysed by quantitative and qualitative methods like arches, loops, whorls, Interdigital areas, Triradial count, ab ridge count, atd angle, and total finger ridge count. Statistical tests like chi square test, and standard error of difference between two means was used. It was observed that radial and ulnar loops, whorls and arches in left hand showed statistically significant difference. Among the quantitative parameters ab ridge count, and atd angle showed statistically significant difference. Remaining parameters did not show statistically significant difference, Thus dermatoglyphic pattern can be used as a cheap modality in screening of masses at risk of Breast cancer. 

Abstract:   The present study highlights the importance of Vitamin D3 and its significance in Diabetes. We have recruited 34 type2 diabetes patients cross sectionally who were on regular treatment between 0-5 years from a Community HealthCare Center in Chennai, after obtaining the informed consent in vernacular language. Blood Investigations on Fasting, Post Prandial & Glycosylated Haemoglobin,Vit D3 levels were measured. Our main aim of this study was to elicit the relationship between Vit D3 and HBA1C. Among those participants 15(44.1%) were females and 19(55.9%) males. Data was analysed using SPSS 16.0, and the mean±SE (mean) of  8 patients who had “Good control” (i.e. HBA1C < 7%) was 16.5±0.82. Among them 3(37.5%) were females & 5(62.5%) were males. For 26 patients who were under ‘Bad Control’ (HBA1C ≥7%), Pearson’s coefficient of correlation between HBA1C and Vit D3 was observed to be negative ‘r = – 0.369’ (P = 0.044), which is yet to be perused with larger sample size.

ABSTRACT:       Background & Objective: Cigarette smoking has become a major avoidable cause of diseases like stroke, Ischemic heart disease and occlusive vascular disease. Smoking increases mortality nearly five times between age group of 30-40 years who are likely to be free from other myocardial risk factors. Hyperthrombic state in smokers may be attributed to enhanced platelet activity which may be reflected in terms of platelet count and platelet aggragabilty. Previous studies have reported many conflicting results on these parameters.The present work was undertaken to study the effect of cigarette smoking on platelet count and platelet aggregability in young & well educated male smokers and compare the results with non-smokers.Methods: Total sample size was 70 which included a mixed population of male doctors & engineers [smokers (n=35) & non-smokers (n=35)] between the age group 26-40 yrs. They were selected on the basis of smoking of filtered cigarettes minimum 5 per day for duration ≤ 10 years. Platelet count was done on Sysmex K-4500 Autoanalyser. Platelet aggragbility was estimated by O’Brien’s method using ADP.  Observations: Our results showed a statistically significant increase in the platelet aggragbility (P< 0.01 & Z >2). The change in the platelet count was statistically insignificant.Conclusion: As per our study increased platelet adhesiveness is evidenced even in young smokers with duration of smoking less than 10 years. Such young population which is otherwise free from the predisposing factors like obesity, hypertension, diabetes etc. can be encouraged to adopt healthier lifestyles and quit smoking so that future health related consequences can be avoided.

Study Of Carotico- Clinoid Foramen In Dry Human Skulls Of Aurangabad District.- Sanobar I. Shaikh, Rahul K. Ukey, Deepak N. Kawale, Chhaya V.Diwan

ABSTRACT  The Carotico-clinoid foramen is an inconstant structure which is formed by the union of the anterior and middle clinoid processes by a ligament known as the carotico-clinoid ligament (CCL) which may be ossified The present study is to know the prevalence of carotico-clinoid foramen in skulls of Aurangabad District.  For the present study, dry unknown human skulls  from Aurangabad district ,were collected in the Department of Anatomy, Government Medical College, Aurangabad. The carotico-clinoid foramen was studied in dry human skulls and was observed for various parameters like complete or incomplete, unilateral or bilateral. The data was analysed statistically with Chi square test. The presence of carotico-clinoid foramen was observed in 100 skulls and was found in 24 skull bones (24%). Complete bilateral carotico-clinoid foramen was found in 2 skulls (2%) and complete unilateral foramen was found in 2 skulls (2%), one on the right side and one on the left side. Incomplete bilateral carotico-clinoid foramen was found in 8 skulls (8%).Incomplete unilateral foramen was found in 8 skulls (8%), on right side, 7 skulls (7%) and left side, 1 skull (1%). Bilateral carotico-clinoid foramen, complete right side and incomplete left side was observed in 2 skulls (2%). Bilateral caritico-clinoid foramen, complete left side and incomplete right side was observed in 2 skulls (2%). Variations in the anterior  clinoid process (ACP) other than ossification are rare. The ossified carotico-clinoid ligament (CCL) may have compressive effects on the internal carotid artery. Thus anatomical knowledge of anterior clinoid process (ACP) and the clinoid space is of utmost importance for a neurosurgeon approaching the internal carotid artery or other skull based surgery.  Excision of the ACP may be required for many skull based surgical procedures and the presence of any anomalies such as ossified (CCL) may pose a problem for neurosurgeons.

PROFILE OF POISONING IN A TERTIARY CARE HOSPITAL – Srinivasa V,Kavya S.T,Madhumathi R, Amogh Dudhwewala

ABSTRACT Aims – The aim of this prospective study was to analyze the rate and characteristics of acute poisoning cases admitted to adult intensive care unit (ICU).We report the socio-demographic, laboratory, and clinical features of cases, mortality rate, and the results of our treatment modalities.Methods – The study was done in patients admitted with history of poisoning in the department of medicine at Victoria Hospital, Bengaluru from January 2011 to December 2011.This study includes 81 consecutive poisoning Patient who were admitted to ICU care. Detailed history and clinical examination were done in all patients. Ventilator support was given to required patient.Results – Most of the cases were organophosphorus compound poisoning(n=61, 71.3%). Others had consumed drugs which included analgesics, amitryptilne,decongestants, antihypertensives, benzodiazepines.3 had consumed aluminium phosphide and all 3 of them died. The most common indication for mechanical ventilation was respiratory failure which mainly consisted of OP poisoning.Conclusion – Pesticides were the major cause of poisoning(80.2%), the reasons being agriculture based economic, poverty and easy availability of highly toxic pesticides.The poisoning related mortality could be decreased by improving ICU condition and appropriate supportive care.

STUDY OF ANXIETY LEVELS IN YOUNG FEMALE ADOLESCENTS – Bagavad Geetha. M*, Roopa. S, Subhashini. A.S, Janani S

ABSTRACT Background: Anxiety can be a general feeling of worry, a sudden attack of panicky feelings, or a fear of a certain situation or object. Children and teens have anxiety in their lives and like adults, they can suffer from anxiety disorders too. Aim: To assess the degree of Anxiety levels in young female adolescents by using a self-administered  anxiety questionnaire. Methods: This study was conducted in the department of Physiology, Sri Ramachandra Medical College & Research Institute, Chennai among 50 healthy young female students.  Males were excluded in this study. Their age group ranged between  17 to 19. Anxiety status was assessed by using Hamilton Anxiety (HAM-A) Rating Scale questionaire and it was scored. Results: Results showed that 64 % students scored moderate anxiety levels and 36% students scored mild anxiety levels. Conclusion: Based on the results, we have found that mild to moderate anxiety is seen among the young medical students. This could be due to psychophysiological factors like stress that may lead into anxiety and also due to new environmental study.

Key words:   Anxiety, stress, young students

Abstract :Introduction: Today’s medical education system aims at imbibing new Teaching-Learning methods so as to fulfill the national goal of health for all under MCI Vision 2015. Physiology is the backbone of medical knowledge and a better understanding of the subject can be achieved when integrated with Anatomy and Biochemistry. Aim and Objectives: The present study was conducted to compare integrated teaching with traditional lecture method for First MBBS students in our institution. Material and Methods: Out of 100 students 82 students participated in the study voluntarily. Two study groups each of 41 students were formed. Group I was exposed to integrated teaching and Group II to traditional lecture method. A test was conducted subsequently and the data was analyzed using students unpaired t test. Feedback questionnaire form was obtained from students and teachers.

PRIMARY RETROPERITONEAL BRONCHOGENIC CYST MIMICKING HYDATID CYST – A CASE REPORT

ABSTRACTBronchogenic cyst are generally found in mediastinum ,particularly  posterior to carina, but they rarely occur in unusual sites  such as skin, subcutaneous tissue, pericardium and  retroperitoneum. Bronchogenic cysts can in fact mimic hydatid cysts particularly in endemic areas like india. We report a case of retroperitoneal bronchogenic cyst mimicking a hydatid cyst in retroperitoneal location.  A 45-year-old man was admitted to our hospital with complaint of pain in right iliac fossa. CECT of abdomen showed abdominopelvic retroperitoneal cystic mass lateral to right psoas muscle and anterior to right iliacus muscle.CECT findings were suggestive of hydatid cyst. Under general anesthesia, exploratory laprotomy and excision of the retroperitoneal cyst was done.  Histopathological findbronchings were that of bronchogenic cyst.   Most bronchogenic cysts have a benign nature, but malignant changes have also been reported. Therefore, if a cystic tumor in the abdomen is suspected during preoperative diagnosis, a bronchogenic cyst should be considered in the differential diagnosis. Although most are asymptomatic, excision is recommended to establish a definite diagnosis, alleviate any symptoms and to remove the documented risk of malignant transformation.